10 Side Effects of Diuretics
Side Effect #6: Metabolic Alkalosis
Metabolic alkalosis is the condition where the pH is elevated beyond the normal range (pH 7.35–7.45). The mechanism of metabolic alkalosis involves decreased concentration of hydrogen ions or increased bicarbonate concentrations.
Signs and symptoms of metabolic alkalosis include neuromuscular irritability, abnormal sensations, abnormal heart rhythms, tetany, seizures, coma, and confusion that waxes and wanes. Some examples of conditions that may cause metabolic alkalosis are severe vomiting, side effects of diuretics (thiazides and loop diuretics), congenital chloride diarrhea, and cystic fibrosis.
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