10 Side Effects of ACE Inhibitors
Reviewed: Dr. Mera
Side Effect #7: Renal Impairment
Renal or kidney impairment has been reported to be a significant potential side effect of all ACE inhibitors due to their mechanism of action. Those who start using ACE inhibitors will usually have some reduction in the glomerular filtration rate, which generally stabilizes after several days.
However, in individuals with conditions where there is decreased renal perfusion such as polycystic kidney disease, renal artery stenosis, volume depletion, or heart failure, the glomerular filtration rate reduction may be significant. In these patients, the glomerular filtration rate maintenance depends on the angiotensin-II-dependent efferent vasomotor tone.
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