10 Side Effects of ACE Inhibitors
Side Effect #10: Pregnancy Side Effects
While there are some drugs that have been proven to be safe if taken during pregnancy, ACE inhibitors have been shown to cause side effects if taken during any of the trimesters of pregnancy. It has been reported to cause neonatal deaths, stillbirths, congenital malformations, oligohydramnios, hypotension, renal dysplasia, intrauterine growth retardation, patent ductus arteriosus, pulmonary hypoplasia, and incomplete ossification of the skull.
ACE inhibitors are not safe during pregnancy (C – D category) and should be discontinued if pregnancy is suspected. The most serious side effects during pregnancy occur during exposure in the second and third trimester. ACE inhibitors also enter breast milk; therefore, they are not recommended during lactation either.
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