10 Hemochromatosis Symptoms
Symptom #5: Skin Hyperpigmentation or Bronzing
Hyperpigmentation of the skin refers to darkening of the skin. It can be caused by sun damage, Addison’s disease, Cushing’s disease, acanthosis nigricans, melasma, and more. In hemochromatosis, patients experience skin bronzing or hyperpigmentation due to the combination of melanin and iron deposition which is characteristic.
It is one of the classic triad symptoms with the other two being cirrhosis and diabetes in the late stages of the disease. This usually occurs only when the total iron content in the body is more than 5 times the normal levels.
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