What Is Sotos Syndrome?

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By jolene
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6. Inheritance

Although approximately 95% of Sotos syndrome cases are due to spontaneous mutation, there are several families that have more than one affected family member. Unaffected parents have less than 1% chance of having another child with Sotos syndrome.

In the inherited cases, the study of these cases have enabled researchers to conclude that Sotos syndrome is inherited via the autosomal dominant pattern. Dominant genetic disorders occur when only one copy of the abnormal gene is required to cause disease. The risk of passing on the abnormal gene from an affected parent is 50% with equal risk for both males and females.

Sotos Syndrome

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