What Is Sotos Syndrome?
4. Other Signs and Symptoms
Other signs and symptoms of Sotos syndrome include jaundice in newborns and difficulty feeding. In 8% to 35%, heart defects are also often present but are generally not severe. In about 20%, they experience anomalies in the genitourinary system.
Other issues include conductive hearing loss, strabismus, scoliosis (40%), premature eruption of teeth (60% to 80%), and seizures. It has also been estimated that about 2.2% to 3.9% of those with Sotos syndrome develop tumors such as neuroblastoma, acute lymphoblastic leukemia, presacral ganglioma, and sacrococcygeal teratoma. However, there is no single form of cancer that is associated with the condition.
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