10 Side Effects of Acetaminophen
7. Stevens-Johnson Syndrome
Stevens-Johnson Syndrome is a type of hypersensitivity reaction that usually involves the skin and mucous membranes. It can be caused by infectious diseases, drugs, and it can be associated with certain malignancies as well. The early stages of this disease are associated with mild headaches and malaise. Eventually, the characteristic rash appears with the usual target-like appearance. The rash can be seen anywhere in the body but the palms, soles, and the dorsum of the hands are most commonly affected.
Antibiotics are the most common culprit of drug-induced Stevens-Johnson Syndrome, followed by non-steroidal anti-inflammatory drugs and other analgesics like acetaminophen. This is a rare side effect associated with acetaminophen but it can be seen, especially in patients with underlying liver disease.
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