Pellagra Symptoms, Causes and More

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By errol
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Reviewed: dr. vanta
Article Sources Article Sources
  • 1. Piqué-Duran, E, et al. 'Pellagra: a Clinical, Histopathological, and Epidemiological Study of 7 Cases.' Actas Dermo-Sifiliograficas, U.S. National Library of Medicine, 2012, www.ncbi.nlm.nih.gov/pubmed/21737056
  • 2. S;, Savvidou. 'Pellagra: a Non-Eradicated Old Disease.' Clinics and Practice, U.S. National Library of Medicine, pubmed.ncbi.nlm.nih.gov/24847436/
  • 3. 'Pellagra' - American Osteopathic College of Dermatology (AOCD). www.aocd.org/page/Pellagra
  • 4. 'PELLAGRA' - WHO. www.who.int/nutrition/publications/en/pellagra/prevention/control.pdf
  • 5. 'Home.' Home - Libraries, library.uab.edu/locations/reynolds/collections/regional-history/pellagra/history
  • 6. 'Niacin – Vitamin B3.' The Nutrition Source, 6 July 2020, www.hsph.harvard.edu/nutritionsource/niacin-vitamin-b3/
  • 7. Prabhu, Dhanashree, et al. 'Pellagra a Review Exploring Causes and Mechanisms, Including Isoniazid‐Induced Pellagra.' Wiley Online Library, John Wiley & Sons, Ltd, 2 Feb. 2021, onlinelibrary.wiley.com/doi/10.1111/phpp.12659
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Diagnosis

A physical examination is the first step in diagnosing pellagra. Doctors will evaluate the rash, although some rare cases don't present dermatological symptoms. Doctors ask about medical history and daily habits, as well.3‘Pellagra’ - American Osteopathic College of Dermatology (AOCD). www.aocd.org/page/Pellagra

A dietary survey can help identify nutritional deficiencies. Laboratory tests assessing tryptophan levels in the bloodstream and metabolites in urine are rarely used. Sometimes niacin is administered for a few days to distinguish between primary or secondary pellagra. Doctors may consider secondary pellagra if niacin doesn't improve symptoms.1Piqué-Duran, E, et al. ‘Pellagra: a Clinical, Histopathological, and Epidemiological Study of 7 Cases.’ Actas Dermo-Sifiliograficas, U.S. National Library of Medicine, 2012, www.ncbi.nlm.nih.gov/pubmed/21737056

Pellagra

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