10 Melatonin Side Effects
Melatonin Side Effect #8: Over Sedation
It may not be a wise idea to combine melatonin with drugs that are known to be sedatives or that decrease the rate of breathing because the mixture can lead to over-sedation. While it’s not likely that melatonin could directly cause an overdose, it’s still a risk that you won’t want to take.
Even natural herbal supplements can cause oversedation when combined with melatonin, though the risk is much less. These supplements can include things like passion flower or valerian root, which are fairly effective sleep aids on their own.
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