Celiac Disease Causes
Article Sources
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1. Genes
There are only two confirmed causes of celiac disease. The first and most common cause is genetics. It almost always occurs in people with the gene variants DQ2 and DQ8, which help form proteins in the body. However, having these variants isn’t anything close to a guarantee people will get the disease, as only 3% of those with these variants will develop the disease.3‘Symptoms & Causes of Celiac Disease.’ National Institute of Diabetes and Digestive and Kidney Diseases, U.S. Department of Health and Human Services, 1 Oct. 2020, www.niddk.nih.gov/health-information/digestive-diseases/celiac-disease/symptoms-causes.
Still, people who don’t have these variants are much less likely to develop celiac disease at any point in their lives. There may be other genes that contribute to the likelihood of developing the autoimmune disease, but studies are ongoing.
