Carcinoid Syndrome Symptoms
Reviewed: Dr. Mera
10. Irritability
Irritability is a symptom, which is found in several illnesses. It can be understood as a disproportionate reactivity to negative emotional stimuli, frequently resulting in frustration and anger.
Irritability is an uncommon symptom of carcinoid syndrome; however, if present, it can greatly impact the patient’s quality of life. The cause of this symptom is related to the excess production of serotonin by carcinoid tumors. This depletes the available pool of tryptophan in the cerebrospinal fluid, the sole precursor for the synthesis of serotonin in the brain. Moreover, aggression and lack of impulse control have also been associated with carcinoid syndrome.
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