What Are Interleukins?

By jolene

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9. Interleukins in Cancer

Interleukin 22 has been observed to play a role in wound healing and tissue modeling. Specifically, interleukin 22 decreases the destruction of signaling pathways and increases production of antimicrobial molecules that enhance defense and tissue regeneration. It has also been found to be associated with different cancers such as those of the pancreas, lung, gastric, colon, and breast. Interleukin 22 is produced by innate lymphoid cells and T cells. One study concluded that interleukin 22 plays an important role in tissue regeneration and defense through the promotion of cell proliferation, migration, angiogenesis, and more. However, these functions can be used by cancer cells to increase the progression of cancer. New anti-interleukin 22 therapies may be able to help prevent the progression of tumors.