10 Causes of Diverticulitis
Cause #1: Genes
There are some genetic conditions that can cause the formation of diverticula. Examples include Coffin-Lowry syndrome, Ehlers-Danlos syndrome, Williams-Beuren syndrome, and polycystic kidney disease. The affected individuals usually develop diverticula at a young age as these syndromes cause a defect in the connective tissue fibers or extracellular matric components.
Several case reports and studies have suggested that there is a genetic susceptibility to diverticulitis. According to studies of twins and siblings, more than 50 percent of potential risk originates from genetics.
