10 Caffeine Withdrawal Symptoms
Symptom #6: Fatigue
Taking caffeine brings about a feeling of stimulation and as, mentioned earlier, increased alertness and concentration. These effects are due to the interaction of caffeine with some protein targets known as receptors for the chemical adenosine.
When caffeine binds to these receptors, it prevents adenosine from accessing and binding to them. Binding of adenosine to the receptors is associated with feelings of drowsiness and fatigue, a characteristic manifestation among people undergoing caffeine withdrawal. In a study of over 200 people who were regular caffeine consumers, abstaining from caffeine for a period of 16 hours was shown to cause feelings of fatigue.
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