What Is Scalp Psoriasis?
3. Genetic Factors
Patients with a positive family history of psoriasis have a higher risk of developing this condition. However, in most cases, the triggering event may be unknown and is likely immunologic. Researchers have reported that psoriasis commonly begins after an upper respiratory tract infection.
Psoriasis has been associated with some human leukocyte antigen (HLA) alleles with the most prominent being the human leukocyte antigen Cw6 (HLA-Cw6). Some cases of psoriasis are also autosomal dominant. Other HLA antigens associated with psoriasis include HLA-B13, HLA-B17, HLA-B27, and HLA-DR7. The deletion of two late cornified envelope (LCE) genes such as LCE3B and LCE3C have also been found to be a common genetic factor that increases the susceptibility to psoriasis.
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