What Is Empty Sella Syndrome?
2. What Causes This Condition?
Primary empty sella syndrome has no known causes. The current hypothesis is that it results from a congenital disability in the diaphragma sellae, the membrane covering the sella turcica. Researchers believe that some people are born with a tear in the membrane, allowing cerebrospinal fluid to leak into the sella turcica. However, there is no definitive causal link, meaning that a torn diaphragma sellae may only present a higher risk of developing the condition.
Unlike primary empty sella syndrome, doctors know that secondary empty sella syndrome results from another condition. For example, patients who experience head trauma, infection or pituitary tumors may develop this disorder. Multiple underlying brain or pituitary syndromes, like intracranial hypertension or hypophysitis, also present a higher risk for developing empty sella syndrome.
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