What Causes Cold Sores?
Article Sources
- 1. Tan, J. (2017, August 18). Is stress causing your cold sores? Www.Avogel.co.uk. https://www.avogel.co.uk/health/immune-system/cold-sores/is-stress-causing-your-cold-sores/
- 2. World. (2020, January 5). Herpes simplex virus. Who.Int; World Health Organization: WHO. https://www.who.int/news-room/fact-sheets/detail/herpes-simplex-virus
- 3. Hall, O. J., Klein, S. L. (2017). Progesterone-based compounds affect immune responses and susceptibility to infections at diverse mucosal sites. Mucosal Immunology, 10(5), 1097–1107. Nature Research. https://doi.org/10.1038/mi.2017.35
- 4. Cold Sore Triggers: Do Certain Foods Cause Outbreaks? (2020, January 27). Healthline. https://www.healthline.com/health/cold-sore-triggers
5. Hormonal Changes
Hormonal changes, especially female sex hormones, can make individuals more susceptible to both contracting herpes and having a herpes outbreak. Menstrual cycles, pregnancy, menopause, and starting or stopping birth control pills are all examples of potential hormonal changes that can cause cold sores.
This is likely partly due to the fact that a woman’s immune system may dip during the menstruation cycle. In addition, hormonal contraceptives, especially those that primarily contain progesterone, have been linked to a higher susceptibility to herpes.3Hall, O. J., Klein, S. L. (2017). Progesterone-based compounds affect immune responses and susceptibility to infections at diverse mucosal sites. Mucosal Immunology, 10(5), 1097–1107. Nature Research. https://doi.org/10.1038/mi.2017.35
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