What Causes an Enlarged Spleen?
Reviewed: Dr. Gromatzky
3. Other Causes
Other causes of an enlarged spleen include liver problems such as liver cirrhosis, cystic fibrosis, and chronic liver failure. In addition, juvenile rheumatoid arthritis is associated with many organ problems including an enlarged spleen, since it leads to inflammation of the lymph system, which also includes the spleen.
Damage to the spleen due to health issues in other organs of the body, especially the liver and the immune system, can also cause an enlarged spleen.
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