Thiamine Deficiency Signs, Symptoms and More

Author
By paula hart
Reviewed
Reviewed: dr. vanta
Article Sources Article Sources
  • 1. Osiezagha, Kenneth C, et al. 'Thiamine Deficiency and Delirium.' Innovations in Clinical Neuroscience, Matrix Medical Communications, Apr. 2013, www.ncbi.nlm.nih.gov/pmc/articles/PMC3659035
  • 2. Liu M;Alimov AP;Wang H;Frank JA;Katz W;Xu M;Ke ZJ;Luo J; 'Thiamine Deficiency Induces Anorexia by Inhibiting Hypothalamic AMPK.' Neuroscience, U.S. National Library of Medicine, pubmed.ncbi.nlm.nih.gov/24607345.
  • 3. Hammond, Nancy, et al. 'Nutritional Neuropathies.' Neurologic Clinics, U.S. National Library of Medicine, May 2013, www.ncbi.nlm.nih.gov/pmc/articles/PMC4199287
  • 4. BL;, Gratton SM;Lam. 'Visual Loss and Optic Nerve Head Swelling in Thiamine Deficiency without Prolonged Dietary Deficiency.' Clinical Ophthalmology (Auckland, N.Z.), U.S. National Library of Medicine, pubmed.ncbi.nlm.nih.gov/24899800
  • 5. BL;, Gratton SM;Lam. 'Visual Loss and Optic Nerve Head Swelling in Thiamine Deficiency without Prolonged Dietary Deficiency.' Clinical Ophthalmology (Auckland, N.Z.), U.S. National Library of Medicine, pubmed.ncbi.nlm.nih.gov/24899800
Medical Expert Medical Expert

Blurred Vision

Just as the peripheral nerves rely on thiamine, so does the optic nerve. Thiamine deficiency can cause the optic nerve to swell, and severe cases can cause optic neuropathy, resulting in blurred vision or even blindness.

Many people with a thiamine deficiency find that their vision improves when the deficiency is resolved through supplementation.4BL;, Gratton SM;Lam. ‘Visual Loss and Optic Nerve Head Swelling in Thiamine Deficiency without Prolonged Dietary Deficiency.’ Clinical Ophthalmology (Auckland, N.Z.), U.S. National Library of Medicine, pubmed.ncbi.nlm.nih.gov/24899800 The longer the deficiency goes undetected, the greater the risk of long-lasting or permanent damage to the optic nerve.

Thiamine Deficiency

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