Thiamine Deficiency Signs, Symptoms and More

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By paula hart
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Reviewed: dr. vanta
Article Sources Article Sources
  • 1. Osiezagha, Kenneth C, et al. 'Thiamine Deficiency and Delirium.' Innovations in Clinical Neuroscience, Matrix Medical Communications, Apr. 2013, www.ncbi.nlm.nih.gov/pmc/articles/PMC3659035
  • 2. Liu M;Alimov AP;Wang H;Frank JA;Katz W;Xu M;Ke ZJ;Luo J; 'Thiamine Deficiency Induces Anorexia by Inhibiting Hypothalamic AMPK.' Neuroscience, U.S. National Library of Medicine, pubmed.ncbi.nlm.nih.gov/24607345.
  • 3. Hammond, Nancy, et al. 'Nutritional Neuropathies.' Neurologic Clinics, U.S. National Library of Medicine, May 2013, www.ncbi.nlm.nih.gov/pmc/articles/PMC4199287
  • 4. BL;, Gratton SM;Lam. 'Visual Loss and Optic Nerve Head Swelling in Thiamine Deficiency without Prolonged Dietary Deficiency.' Clinical Ophthalmology (Auckland, N.Z.), U.S. National Library of Medicine, pubmed.ncbi.nlm.nih.gov/24899800
  • 5. BL;, Gratton SM;Lam. 'Visual Loss and Optic Nerve Head Swelling in Thiamine Deficiency without Prolonged Dietary Deficiency.' Clinical Ophthalmology (Auckland, N.Z.), U.S. National Library of Medicine, pubmed.ncbi.nlm.nih.gov/24899800
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Increased Irritability

Frustration, agitation and irritability are thought to be symptoms of thiamine deficiency. However, this symptom is sometimes overlooked because irritability can be caused by stress, lack of sleep, premenstrual syndrome and many other conditions.

Researchers have found that irritability can sometimes appear within days or weeks of a person developing a thiamine deficiency.3Hammond, Nancy, et al. ‘Nutritional Neuropathies.’ Neurologic Clinics, U.S. National Library of Medicine, May 2013, www.ncbi.nlm.nih.gov/pmc/articles/PMC4199287 This symptom is noticeable in children who have this deficiency, but it may also appear in adults.

Thiamine Deficiency

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