10 Side Effects of Ibuprofen
8. Edema
Edema is defined as fluid accumulation that leads to swelling of the affected tissue. It is a non-specific symptom associated with many conditions. Depending on the location and the nature of the edema, it can be a very dangerous sign like in pulmonary edema or an annoying symptom like the one seen in venous insufficiency.
Due to its mechanism of action, ibuprofen may cause peripheral edema in the legs in less than 3% of the patients taking it. This is a rare side effect associated with ibuprofen but the longer the treatment, the greater the chances of seeing side effects.
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