10 Pernicious Anemia Symptoms

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By dr. mera
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  • 1. Rodriguez, N. (2020, June 24). Pernicious Anemia. https://www.ncbi.nlm.nih.gov/books/NBK540989/
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Pernicious anemia is an autoimmune condition where the body is unable to make enough intrinsic factor (IF), resulting in inadequate absorption of vitamin B12, which causes anemia. Intrinsic factor is a protein produced in the stomach that plays an important role in vitamin B12 absorption. Vitamin B12 plays an important role in the production of red blood cells, therefore, if a person is not properly absorbing vitamin B12, it may cause their red blood cells to become bigger than usual and eventually break. Vitamin B12 is also involved in the proper functioning of the nerves, therefore, if a person is unable to absorb it, it may cause neurologic complications as well.

This condition affects less than 1% of the population, but it is more common in the elderly (above 60 years of age). People of Celtic and/or Scandinavian origin are more commonly affected by this disease as well.1Rodriguez, N. (2020, June 24). Pernicious Anemia. https://www.ncbi.nlm.nih.gov/books/NBK540989/

1. Weight Loss

Losing weight unintendedly is something that might sound good for some people but it is certainly something that requires checking. Losing large amounts of weight over a short period is something that is not usual and could be a sign that something is wrong.

Patients with pernicious anemia usually experience weight loss. Up to 50% of patients will lose 10 pounds or more. Weight loss might be associated with the reduced appetite commonly seen in patients with this condition. If you are experiencing sudden and unintended weight loss, you should seek medical attention to find out the exact cause.

Pernicious Anemia

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