10 Lupus Symptoms In Women
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8. Swelling of Lymph Nodes
Lymphadenopathy is a medical term that refers to the swelling of lymph nodes, which are small structures that filter substances from the lymphatic system. They are an important component of our immune system, and, as such, certain immune cells (lymphocytes) complete their maturation process and many other functions within these structures. Importantly, lymphadenopathy is nonspecific. For instance, possible causes of this clinical sign include infections, malignancies, and autoimmune conditions. Hence, pinpointing the cause of lymphadenopathy can be challenging.
In SLE, the generalized swelling of lymph nodes is common in children and young adults. However, it is not considered a criterion for the diagnosis of lupus. Lymphadenopathy can be observed in any stage of the course of SLE; although it is most likely indicative of disease activity. Moreover, affected lymph nodes are mainly located in the neck and the axilla, and they are usually painful and soft.
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