10 Causes of Spleen Pain
Reviewed: Dr. Mera
Cause #9: Spleen Cancer
The spleen is a secondary lymphoid organ; thus, it is a common site for the dissemination of malignancies like lymphoma. It can be involved with any lymphoid malignancy; nonetheless, splenic pain due to splenomegaly is rarely the predominant presenting symptom of these diseases. Furthermore, some lymphoma subtypes can present with isolated splenomegaly (i.e. diffuse large B-cell lymphoma, mantle cell lymphoma).
In patients with lymphoma, splenic pain can be associated with unexplained weight loss, fever, night sweats, and fatigue.
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