What Is Hypophosphatasia?

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By amanda
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Reviewed: Dr. Gromatzky
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5. What Are the Symptoms of Childhood Hypophosphatasia?

Those who deal with childhood hypophosphatasia sometimes have their symptoms reappear later in life, while in other cases they may go away. Weakness in the bones of the legs can lead to an awkward gait. This typically manifests at some point between the ages of two and three. Often the baby teeth will fall out earlier than normal.

Bone deformations can lead to numerous problems, including fractures, joint pain and bone pain. These children can develop rickets from as early as two years old. As the skull can be affected, there may be increased pressure in the head, known as intracranial hypertension. Childhood hypophosphatasia is typically less severe than the infantile form.

Hypophosphatasia

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