What Is Hypophosphatasia?

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By amanda
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Reviewed: Dr. Gromatzky
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4. What Are the Symptoms of Adult Hypophosphatasia?

Some people with adult hypophosphatasia lose their teeth, while others may experience pseudogout, which is a sudden pain in the joints. This may be a result of joint inflammation caused by calcific periarthritis, the accumulation of calcium crystals within the cartilage around joints. Pain may also occur in the bones themselves.

People who deal with adult hypophosphatasia typically live their lives with chronic debility and pain. These people are much more likely to sustain stress fractures, particularly around the thighs or feet. During childhood, these people may develop rickets, while into adulthood they often suffer from a bone-softening issue known as osteomalacia.

Hypophosphatasia

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