Neuroleptic Malignant Syndrome Symptoms

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By dr. gromatzky
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  • 1. Berman, Brian D. “Neuroleptic malignant syndrome: a review for neurohospitalists.” The Neurohospitalist vol. 1,1 (2011): 41-7. doi:10.1177/1941875210386491
  • 2. Khan, Zafar, Rajaratnam, R., Singh, Vinod. “Neurogenic bladder in neuroleptic malignant syndrome.” Urology vol. 37,6 (1991): 533-544. Available from: https://www.sciencedirect.com/science/article/pii/0090429591803207
  • 3. Simon LV, Hashmi MF, Callahan AL. Neuroleptic Malignant Syndrome. [Updated 2020 Jun 3]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2020 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK482282/
  • 4. Tse, Lurdes et al. “Neuroleptic Malignant Syndrome: A Review from a Clinically Oriented Perspective.” Current neuropharmacology vol. 13,3 (2015): 395-406. doi:10.2174/1570159x13999150424113345
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9. Lab Values

Lab values offer clinicians an idea of what may be going on within the body. They are found by testing levels of certain chemicals, compounds, cells, etc. within a patient’s blood, urine, cerebral spinal fluid, and others. The specific lab that the clinician orders to be drawn will depend upon what they suspect is wrong with the patient and then used to help confirm the diagnosis.

In some cases of NMS, a test ordered by the doctor will reveal an increased level of creatine phosphokinase which indicates the breaking down of skeletal muscle (rhabdomyolisis) and also an increased level of white blood cells (leukocytosis). Excessive and prolonged break down of skeletal muscle could cause kidney (renal) failure. The doctor may also find that the patient is deficient in iron and in a state of metabolic acidosis, which is essentially when the body has a higher pH.1Berman, Brian D. “Neuroleptic malignant syndrome: a review for neurohospitalists.” The Neurohospitalist vol. 1,1 (2011): 41-7. doi:10.1177/1941875210386491

Neuroleptic Malignant Syndrome

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