Neuroleptic Malignant Syndrome Symptoms

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By dr. gromatzky
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  • 1. Berman, Brian D. “Neuroleptic malignant syndrome: a review for neurohospitalists.” The Neurohospitalist vol. 1,1 (2011): 41-7. doi:10.1177/1941875210386491
  • 2. Khan, Zafar, Rajaratnam, R., Singh, Vinod. “Neurogenic bladder in neuroleptic malignant syndrome.” Urology vol. 37,6 (1991): 533-544. Available from: https://www.sciencedirect.com/science/article/pii/0090429591803207
  • 3. Simon LV, Hashmi MF, Callahan AL. Neuroleptic Malignant Syndrome. [Updated 2020 Jun 3]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2020 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK482282/
  • 4. Tse, Lurdes et al. “Neuroleptic Malignant Syndrome: A Review from a Clinically Oriented Perspective.” Current neuropharmacology vol. 13,3 (2015): 395-406. doi:10.2174/1570159x13999150424113345
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10. Urinary Incontinence or Retention

Urinary incontinence describes the inability to retain urine within the bladder. Incontinence can occur from the bladder simply being too full and waiting too long, a neurological problem, a change in position of the bladder, or pelvic floor issues, etc. Urinary incontinence that is due to something wrong within the nervous system is called neurogenic bladder. Neurogenic bladder can cause either difficulty with holding urine in (incontinence) or difficulty letting urine out (retention).

Neurogenic bladder is the cause of urinary incontinence (or retention) in those with NMS due to the reduced dopamine within the brain.2Khan, Zafar, Rajaratnam, R., Singh, Vinod. “Neurogenic bladder in neuroleptic malignant syndrome.” Urology vol. 37,6 (1991): 533-544. Available from: https://www.sciencedirect.com/science/article/pii/0090429591803207 This can be a very frustrating and shocking sign for someone to experience especially if it is not something that they are used to.

Neuroleptic Malignant Syndrome

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