10 Aplastic Anemia Symptoms
Symptom #3: Malaise
Malaise is a general feeling of discomfort, uneasiness, pain, and is often one of the earliest indications of an underlying disorder. It is a vague and nonspecific symptom that can be seen in hunger, emotional stress, internal bleeding, cancer, stroke, and various conditions.
Patients often describe malaise as a feeling of “something is not feeling right.” This can become a challenge for medical professionals to diagnose or determine the significance of malaise. Malaise is thought to be due to the activation of an immune response where there is the production and release of pro-inflammatory cytokines.
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