10 Symptoms of Addison's Disease
Symptom #6: Loss of Weight
In addition to fatigue, Addison’s disease can lead to a steady loss of weight. This can be attributed to several factors, one of which is poor appetite. The body requires a certain amount of nutrients to function and to maintain a healthy weight. If your body uses more nutrients than you get from the food that you eat, it may have to get the balance from its tissues.
Low production of cortisol hormones adversely affect the functions of leptin and ghrelin hormones, which have a role in appetite stimulation. This means that these hormones do not stimulate hunger or the appetite necessary to cause you to eat. You may end up eating less than your body needs. Sustained poor appetite leads to loss of weight.
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