What Is Motor Neuron Disease?
Reviewed: Dr. Gromatzky
1. Signs and Symptoms
The signs and symptoms of MNDs depend on the specific type of disease but the symptoms are generally movement related. The symptoms tend to begin gradually and worsen after several months. Besides muscle weakness, other symptoms include muscle spasms and muscle cramps.
Depending on the type of disease, there can also be difficulty breathing during exertion, orthopnea, respiratory failure, difficulty swallowing, difficulty speaking, excessive saliva production, emotional disturbance, behavioral changes, and more. Some patients also experience muscle wasting, increased muscle tone, cognitive changes, and loss of ability to move.
