What Is Motor Neuron Disease?
Motor neuron diseases (MNDs) is a term used to categorize a group of diseases where neurodegeneration selectively affects the motor neurons leading to loss of voluntary control of the body’s muscles. Based on the International Classification of Diseases 11 (ICD-11), some of the following disorders are categorized under MNDs: pseudobulbar palsy, primary lateral sclerosis, amyotrophic lateral sclerosis, progressive bulbar palsy, progressive muscular atrophy, and monomelic amyotrophy.
MNDs can be divided into sporadic and hereditary diseases. They can also be grouped into those that mainly affect the upper motor neurons, lower motor neurons, or both. Although different diseases affect patients differently, it leads to movement-related issues such as muscle weakness.
