What Is Mastocytosis?
7. Consultations
In some cases of mastocytosis, a consultation may be required for staging and bone marrow biopsy. As per the WHO classification of systemic mastocytosis, several staging investigations help define the disease subtype.
When the serum tryptase level is more than 200 ng/ml or there is more than 30% bone marrow mastocystosis burden, it is indicative of a high systemic mastocytosis burden. Hemoglobin levels less than 10 g/L, absolute neutrophil count less than 1000 g/L, platelet count less than 100,000 g/L, palpable spleen due to enlargement with hypersplenism, liver enlargement with ascites and impaired liver function, malabsorption with low albumin and weight loss, and osteolysis or severe osteoporosis can result in life-threatening organopathy or pathologic fractures.
Advertisement
