What Is Mastocytosis?
5. Medication
Treatment for mastocytosis tends to be conservative and supportive. It includes symptomatic relief. Patients should avoid triggers and medications that precipitate the release of mediators.
Medication includes the use of H1 and H2 antihistamines, oral disodium cromoglycate, cautious administration of aspirin, leukotriene antagonists, mast cell stabilizers, proton pump inhibitors, salbutamol, epinephrine, corticosteroids, and antidepressants. In advanced disease, cytoreductive therapy such as alpha interferon, cladribine, and tyrosine kinase inhibitors may be beneficial as well.
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