What Are NSAIDS?
Reviewed: Dr. Gromatzky
2. COX-1
NSAIDs help to prevent certain enzymes from having an effect on the body. They focus on the cyclooxygenase enzyme, also known as COX, and this enzyme has 2 types, COX-1 and COX-2. COX-1 is an enzyme that helps to protect the stomach lining from stomach juices that would otherwise be corrosive to the stomach. COX-1 also helps the kidney to function properly.
Some NSAIDs will block the COX-1 enzyme in particular. While these can help to reduce inflammation, they can cause unwelcome symptoms with the digestive system. Common types of these include ibuprofen and paracetamol, which will inhibit COX-1 as well as COX-2.
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