10 Symptoms of Osteomyelitis
Symptom #9: Malaise
Malaise is an uneasy sensation where there is general discomfort. It is often one of the earliest indications of disease. It is a non-specific symptom that can be seen in hunger, cancer, stroke, internal bleeding, heart attack, infections (viral, bacterial, parasitic), and more.
Patients with malaise often describe it as an uneasiness where they feel “something is not right”. Experts believe that malaise is due to the activation of the immune response and release of proinflammatory cytokines.
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