10 Histoplasmosis Symptoms
Symptom #2: Chills
Chills refer to a feeling of coldness when one has a fever. However, in some cases, it can also be a symptom that occurs alone. In fever, it is due to the release of prostaglandins and cytokines as part of an inflammatory response. This response increases the set point of body temperature, which leads to the feeling of coldness until a new point is reached.
During chills, shivering may also occur as this helps produce heat and increase the body temperature. Chills are seen in inflammatory diseases such as malaria and flu.
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