10 Causes of Dystonia
Cause #9: Leigh Disease
Leigh syndrome or Leigh disease is an inherited condition that affects the central nervous system. In this condition, there is a lack or absent amount of thiamine triphosphate, thought to be due to a blockage in the thiamine diphosphate kinase enzyme. This means that treatment of this condition would be to take thiamine triphosphate daily.
Symptoms in Leigh disease can begin as early as infancy and as more cases are being recognized, it has been observed that symptoms can begin at any age and patients may survive for many years after diagnosis. Symptoms include diarrhea, vomiting, failure to thrive, dysphagia, irritability, dystonia, hypotonia, ataxia, and more.
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