What Is Peyronie's Disease?
7. Medical Therapy
The best medical therapy for this condition has yet to be identified. Watchful observation without any intervention is acceptable for those with minimal symptoms and if it does not disrupt sexual function. A study involving 246 patients with Peyronie’s disease found that the condition improved in 12% of patients, unchanged in 40%, and worsened in 48%.
All who initially presented with penile pain have reported improvement with 89% noting complete resolution of pain without any treatment. In the evaluation of a specific therapy, placebo effect should be taken into consideration as some symptoms can spontaneously improve in many patients. Some medications and supplements that have been used are vitamin E supplements, interferon-alpha-2b, and collagenase clostridium histolyticum.
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