What Is Peyronie's Disease?

Peyronie’s disease is a condition named after Francois Gigot de la Peyronie, a French surgeon who first described this condition in 1743. This condition is characterized by a curvature in the penile shaft resulting in various issues. It is a connective tissue disorder where there is abnormal growth of fibrous plaques in the penile soft tissue.

Throughout the years, there have been various medications and surgical therapies used in the treatment of this condition. The number of methods proposed is a testament to how ineffective these treatments have been. This condition is due to the presence of scar tissue that affects the connective tissue in the penis. The curvature is usually obvious when there is erection but can be noticeable even when flaccid. The area of fibrosis known as the plaque can vary in firmness and become calcified.

1. Epidemiology

The rate of Peyronie’s disease has been estimated to be about 0.39% to 3%. However, this may be an underestimation as most men are embarrassed regarding this issue. There may also be underreporting due to mild or non-debilitating issues where medical attention is not required. Although most commonly seen in men between the ages of 40 to 70 years old, there are also other authors that reported these cases among young individuals. In a study involving 4,432 study participants, it was reported that the estimated prevalence by age was 1.5% for those 30 to 39, 3% for men 40 to 49, 3% for men between the ages of 50 to 59, 4% for those 60 to 69, and 6.5% for men above the age of 70 years.

What Is Peyronie's Disease?

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