Zellweger Syndrome Symptoms
7. Skeletal Abnormalities
Besides the craniofacial deformities that have been mentioned, a baby with Zellweger syndrome will also tend to suffer bone defects in the hands, legs, and feet. They often have low bone density and will experience chondrodysplasia punctata.
This condition stunts growth and can contribute toward mental infirmity, itchy and scaly skin, and cause vision problems. Problems such as clubfoot are another common sign of skeletal abnormalities. Contracture deformities also affect the stability and support of joints. These affect the muscles, tendons, and ligaments that are responsible for facilitating smooth joint movement. Orthopedic treatment is often required throughout the life of the child.
Advertisement
