What Is Leaky Gut Syndrome?

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By brett
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  • 1. Meddings, J.B., J. Jarand, S.J. Urbanski, J. Hardin and D.G. Gall. Increased gastrointestinal permeability is an early lesion in the spontaneously diabetic BB rat. American Journal of Physiology. 1999 Apr;276(4):G951-7. doi:10.1152/ajpgi.1999.276.4.G951.
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8. Unsupported Claims

Excess permeability in the gut, or a leaky gut, does occur, though there is controversy over whether it is the cause or symptom of associated diseases. There are some claims, however, that have yet to find widespread support from scientific study. Autism, depression, anxiety and cancer are all medical conditions that have been linked to leaky gut syndrome without clear scientific support.

Much of the research on these conditions are inconsistent in the results between them. While some studies indicate a high degree of permeability in individuals with the condition, others find that the gut’s tight junctions are normal. More research is necessary before linkages between a leaky gut and many health conditions can be established or refuted.

Leaky Gut Syndrome

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