What Is Leaky Gut Syndrome?

By brett
Article Sources Article Sources
  • 1. Meddings, J.B., J. Jarand, S.J. Urbanski, J. Hardin and D.G. Gall. Increased gastrointestinal permeability is an early lesion in the spontaneously diabetic BB rat. American Journal of Physiology. 1999 Apr;276(4):G951-7. doi:10.1152/ajpgi.1999.276.4.G951.
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2. Causes

Thus far, the precise causes are unknown. The single protein associated with gut permeability, zonulin, is activated in people who are genetically predisposed to the condition. Gluten and bacteria are the two triggers that seem to activate the zonulin protein.

There are a number of factors that may contribute to the development of leaky gut syndrome. Nutrient deficiencies, inflammation and poor gut health are all possible causes. Chronic stress may be a contributing factor. In addition, consuming excessive amounts of sugar and alcohol may lead to the condition, as well as the long-term use of non-steroidal anti-inflammatory drugs.

Leaky Gut Syndrome

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