What Is Erythema Multiforme?
3. Erythema Multiforme Major
Erythema multiforme major presents with more signs and symptoms than the minor form. People with major forms often experience symptoms 1-14 days before the rash begins, which include fever, sore throat, cough, diarrhea, vomiting, and chest pain.
In this form, the skin lesions appear in a similar distribution than in the mild form of erythema multiforme (i.e. they are symmetrical and they start in the extremities). Frequently, the rash affects the mucus membranes, appearing most often on the interior of the cheeks and the lips, which may affect activities like eating or drinking. Additionally, inflammation of the clear tissue that covers the white part of the eye (conjunctivitis) can also occur, resulting in abnormal tear secretion (lacrimation), extreme light sensitivity, a burning sensation in the eyes, and visual impairment. Finally, genitourinary and tracheal lesions may also occur.
Advertisement
