What Is Anhidrosis?

By jolene
Reviewed: Dr. Mera
Feb 13, 2020
Medical Expert Medical Expert

Anhidrosis or hypohidrosis refers to the condition where there is diminished or absent sweating despite presence of appropriate stimuli. In anhidrosis, there is complete absence of sweating while in hypohidrosis, there is less sweating compared to a normal individual.

Anhidrosis often leads several consequences as it means that the body is unable to sweat like normal individuals. This means that the body is unable to cool itself. Anhidrosis or hypohidrosis is in contrast with hyperhidosis, which is excessive sweating. Hyperhidrosis is usually a benign condition that causes mainly social consequences.

1. Causes of Anhidrosis or Hypohidrosis

Some of the causes of anhidrosis or hypohidrosis include the side effects of medications such as anticholinergic agents, carbonic anhydrase inhibitors, tricyclic antidepressants, and botulinum toxin. It can also be caused by radiation, burns, scars, sores, surgery, and tumors. Some skin conditions that can cause this issue include systemic sclerosis, graft versus host disease, Sjogren syndrome, Fabry disease, psoriasis and more. Other conditions that can be possible causes are diabetes mellitus, Horner’s syndrome, amyloidosis, alcoholism, encephalitis, cervical myelopathy, dementia with Lewy bodies, and multiple sclerosis.


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