What Is a Frozen Shoulder?
9. Investigational Therapy
An injection treatment known as collagenase clostridium histolyticum (CCH) is approved by the United States Food and Drug Administration for adult patients with Dupuytren contracture. This has been used as a trial in patients with frozen shoulder and has been reported to be well-tolerated and effective compared to exercise. However, more studies will be necessary.
Extracorporeal shockwave therapy (ESWT) has also shown promise for the treatment of frozen shoulder. It has been found to be favorable compared to oral steroids as short-term treatment in a randomized controlled trial. During the 4th week of treatment, the ESWT group had significant treatment compared to those taking steroids. By the 6th week, the improvement in activities of daily living was significantly better than the steroid group. Researchers believe that ESWT may be a safer alternative compared to steroid injections or surgery.
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