What Does the Spleen Do?
Reviewed: Dr. Gromatzky
8. Sickle Cell Disease
Sickle cell disease can interfere with the working of the spleen. This happens because the sickled cells can be trapped within the spleen. This can lead to injury within the tissues of the spleen. It can also lead to splenic sequestration crisis, which can cause serious anemia that may necessitate blood transfusion.
Sickle cell disease can also damage the spleen, and cause splenomegaly and spleen dysfunction. This is the reason why a person with sickle cell disease is at a high risk of infection.
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