What Causes Moles?
2. Composition
Melanocytic nevi are benign growths or hamartomas (tumor-like nodule) that are composed of melanocytes, which are cells that produce pigments. Melanocytes originate from the neural crest and migrate during development to sites such as the central nervous system, skin, ears, and eyes.
These cells produce melanin, a dark pigment mainly responsible for skin color. Moles at birth are thought to be an anomaly during development and can be considered as hamartomas or malformations. In contrast, acquired moles are thought of as benign neoplasms. When a melanocytic nevus becomes malignant, it is known as melanoma.
