10 Causes of Spina Bifida
Cause #10: Chromosomal Abnormality
Chromosomal abnormality occurs when there is an extra, irregular, or missing portion of chromosomal DNA. It can be confirmed through genetic testing. It usually occurs if there is an issue with cell division after meiosis or mitosis. A simple example of chromosomal abnormality is Down syndrome where there is an extra copy of chromosome 21. This is why this disorder is also known as trisomy 21.
Chromosomal aberrations have been considered to be a possible cause for spina bifida. Experts have observed that up to 10 percent of fetuses with a neural tube defect have a chromosomal abnormality. The associated abnormalities are triploidy, single-gene mutations, and trisomies 13 and 18.
Advertisement
