10 Causes of Paresthesia
Cause #10: Chemotherapy-Induced Peripheral Neuropathy
Chemotherapy-induced peripheral neuropathy is often a progressive and irreversible condition where the affected individual experiences numbness, tingling, pain, and sensitivity to cold in the extremities. It can also progress to the arms and legs. This condition is estimated to affect 30 to 40 percent of those undergoing chemotherapy. It has been associated with chemotherapy drugs such as thalidomide, ixabepilone, vincristine, vinblastine, paclitaxel, docetaxel, and cisplatin.
It usually occurs after the first dose of chemotherapy and gradually increases in severity as the treatment continues. However, the progression generally stops after completion of treatment. Some cases have been reported to be reversible. The pain can typically be relieved through treatment. However, the numbness has been observed to be resistant to treatment.
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